Publications

Peer-reviewed work and selected preprints

Current lists are also maintained on PubMed and Google Scholar.

Peer-reviewed publications

The Spatial Transcriptional Activity of Hepatic TCF7L2 Regulates Zonated Metabolic Pathways.
Ayala I, et al., including Valdez IA.
Nature Communications 16(1): 3408 (2025).
Persistent Inflammatory Lipotoxicity Impedes Pancreatic β-cell Function in Diet-Induced Obese Mice.
Valdez IA, et al.
bioRxiv (2022). Preprint.
Insulin Resistance is Mechanistically Linked to Hepatic Mitochondrial Remodeling in NAFLD.
Shannon CE, et al., including Valdez IA.
Molecular Metabolism 45: 101154 (2021).
Effect of Mild Physiologic Hyperglycemia on Insulin Secretion, Clearance, and Sensitivity.
Merovci A, et al., including Valdez IA.
Diabetes 70(1): 204–213 (2021).
Dynamic Proteome Profiling of Human Pluripotent Stem Cell-Derived Pancreatic Progenitors.
Loo LSW, et al., including Valdez IA.
Stem Cells (2019).
Insulin Receptor-Mediated Signaling Regulates Pluripotency Markers and Lineage Differentiation.
Gupta MK, et al., including Valdez IA.
Molecular Metabolism 18: 153–163 (2018).
Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation.
Valdez IA, et al.
Cell Reports 15(3): 460–470 (2016).
Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia.
Teo AK, et al., including Valdez IA.
Stem Cell Reports 6(3): 357–367 (2016).
Cellular Stress Drives Pancreatic Plasticity.
Valdez IA, et al.
Science Translational Medicine 7(273): 273ps2 (2015).
Preserved DNA Damage Checkpoint Pathway Protects Against Complications in Long-Standing Type 1 Diabetes.
Bhatt S, et al., including Valdez IA.
Cell Metabolism 22(2): 239–252 (2015).
Comparable Generation of Activin-Induced Definitive Endoderm via Additive Wnt or BMP Signaling.
Teo AK, et al., including Valdez IA.
Stem Cell Reports 3(1): 5–14 (2014).

For a more detailed academic record, including conference presentations and grants, see my CV.